From the advent of female oral contraceptive in 1950s to the birth of test tube baby in 1970s and the successful cloning of Dolly sheep in the late 1990s, reproductive medicine technology has made a major breakthrough Human assisted reproductive technology (Art) is mainly a special technology to help those patients who are still unable to conceive after regular treatment to artificially combine eggs and sperm under laboratory conditions to achieve pregnancy. As this technology completely separates sex and fertility, its rapid development has also brought a series of ethical, legal and social problems, making the development of art very different from other medical disciplines, become a medicine growing up in controversy.
Infertility is a reproductive system disease characterized by failure to conceive clinically after 12 months or more of regular sex without contraception. The global prevalence of infertility has increased from 11% in 1997 to 15.4% in 2018, and is expected to increase to 17.2% in 2023. The prevalence of infertility in the United States is expected to increase from 16% in 2018 to 17.9% in 2023, while the prevalence of infertility in China is expected to increase from 16.0% in 2018 to 18.2% in 2023.